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Study identifier: NCT03945773 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

Condition: Locally Advanced or Metastatic Renal Cell Carcinoma  ·  Sponsor: Ipsen

PhasePhase 2
Planned participants127
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The overall objective of this study is to evaluate the efficacy and safety of cabozantinib as 2nd line treatment in subjects with unresectable, locally advanced or metastatic RCC with a clear-cell component, who progressed after prior Checkpoint Inhibitors (CPI) therapy with ipilimumab and nivolumab in combination or CPI combined with Vascular Endothelial Growth Factor (VEGF)-targeted therapy.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (40)

SALK - Salzburger LandesklinikSalzburg, Austria
CHRU BesançonBesançon, France
Centre Jean PerrinClermont-Ferrand, France
Centre Léon BérardLyon, France
Institut Paoli CalmettesMarseille, France
Institut de Cancérologie de LorraineNancy, France
CHU de Nîmes - Institut de Cancérologie du GardNîmes, France
Institut Mutualiste MontsourisParis, France
Centre Hospitalier Lyon SudPierre-Bénite, France
Institut de Cancérologie de l'OuestSaint-Herblain, France
CHU StrasbourgStrasbourg, France
Institut Claudius RégaudToulouse, France

+ 28 more locations — full list on the registry record.

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