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Study identifier: NCT03940703 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

Condition: Non-small Cell Lung Cancer  ·  Sponsor: EMD Serono Research & Development Institute, Inc.

PhasePhase 2
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study was to assess the antitumor activity, safety, tolerability, and pharmacokinetics (PK) of the Mesenchymal-epithelial Transition Factor (MET) inhibitor tepotinib combined with the 3rd generation EGFR inhibitor osimertinib in participants with advanced or metastatic non-small cell lung cancer (NSCLC).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (179)

Yuma Regional Medical CenterYuma, Arizona, United States
Compassionate Care Research Group Inc - Edinger Medical Group, Inc.Fountain Valley, California, United States
Memorial CareLong Beach, California, United States
Ventura County Hematology Oncology SpecialistsOxnard, California, United States
Innovative Clinical Research InstituteWhittier, California, United States
Eastern Connecticut Hematology & Oncology AssociatesNorwich, Connecticut, United States
Holy CrossFort Lauderdale, Florida, United States
Memorial Healthcare SystemHollywood, Florida, United States
Cancer Specialists of North FloridaJacksonville, Florida, United States
Ocala OncologyOcala, Florida, United States
University Cancer and Blood CenterAthens, Georgia, United States
Hawaii Cancer CareHonolulu, Hawaii, United States

+ 167 more locations — full list on the registry record.

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