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Study identifier: NCT03924856 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Condition: Bladder Cancer  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 3
Planned participants907
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A global study to evaluate peri-operative pembrolizumab with chemotherapy versus placebo to pembrolizumab plus chemotherapy in cisplatin eligible patients.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (175)

Scripps MD Anderson ( Site 0010)La Jolla, California, United States
Providence Saint John's Health Center ( Site 0075)Santa Monica, California, United States
Georgetown University Medical Center ( Site 0022)Washington D.C., District of Columbia, United States
AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlando ( Site 0005)Orlando, Florida, United States
Parkview Cancer Institute ( Site 0077)Fort Wayne, Indiana, United States
Indiana University Melvin and Bren Simon Cancer Center ( Site 0004)Indianapolis, Indiana, United States
Ochsner Medical Center ( Site 0049)New Orleans, Louisiana, United States
New England Cancer Specialists ( Site 0070)Scarborough, Maine, United States
UMass Memorial Medical Center ( Site 0051)Worcester, Massachusetts, United States
Henry Ford Hospital ( Site 0039)Detroit, Michigan, United States
Mercy Hospital Saint Louis ( Site 0064)St Louis, Missouri, United States
Morristown Medical Center ( Site 0015)Morristown, New Jersey, United States

+ 163 more locations — full list on the registry record.

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