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Study identifier: NCT03901963 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant

Condition: Multiple Myeloma  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants200
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate conversion rate to minimal residual disease (MRD) negativity following the addition of daratumumab to lenalidomide relative to lenalidomide alone, when administered as maintenance treatment to anti-cluster of differentiation 38 (CD38) treatment naive participants with newly diagnosed multiple myeloma who are MRD positive as determined by next generation sequencing (NGS) at screening, following high-dose therapy (HDT) and autologous stem cell transplant (ASCT).

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (73)

University of Alabama BirminghamBirmingham, Alabama, United States
Arizona Oncology Associates, PC - HALGlendale, Arizona, United States
Cancer Treatment Center of America PhoenixGoodyear, Arizona, United States
University of California San Diego (UCSD) - The Rebecca and John Moores Cancer CenterLa Jolla, California, United States
UCLA David Geffen School of MedicineLos Angeles, California, United States
University of California San FranciscoSan Francisco, California, United States
Colorado Blood Cancer InstituteDenver, Colorado, United States
Rocky Mountain Cancer CentersDenver, Colorado, United States
University of Colorado HealthFort Collins, Colorado, United States
Yale University Medical CenterNew Haven, Connecticut, United States
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United States
Cancer Specialists of North FloridaJacksonville, Florida, United States

+ 61 more locations — full list on the registry record.

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