EICHOR
● Terminated
Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)
Condition: Urothelial Carcinoma · Bladder Cancer · Sponsor: Hoffmann-La Roche
About this study
A Phase Ib/II, open-label, multicenter, randomized, umbrella study in participants with MIBC and in participants with locally advanced or metastatic Urothelial Carcinoma (UC) who have progressed during or following a platinum-containing regimen. The study is designed with the flexibility to open new treatment arms as new treatments become available, close existing treatment arms that demonstrate minimal clinical activity or unacceptable toxicity, or modify the participant population (e.g., with regard to prior anti-cancer treatment or biomarker status). Participants in the mUC Cohort who experience loss of clinical benefit or unacceptable toxicity during Stage 1 may be eligible to continue treatment with a different treatment regimen for Stage 2.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (33)
| UCLA Department of Medicine | Los Angeles, California, United States | — |
| UCSF Comprehensive Cancer Ctr | San Francisco, California, United States | — |
| Stanford Cancer Center | Stanford, California, United States | — |
| University of Kentucky Chandler Medical Center | Lexington, Kentucky, United States | — |
| Norton Cancer Institute | Louisville, Kentucky, United States | — |
| Memorial Sloan-Kettering Cancer Center | Commack, New York, United States | — |
| Levine Cancer Institute | Charlotte, North Carolina, United States | — |
| University Hospitals Cleveland Medical Center | Cleveland, Ohio, United States | — |
| Cleveland Clinic | Cleveland, Ohio, United States | — |
| The University of Texas MD Anderson Cancer Center | Houston, Texas, United States | — |
| Centre Francois Baclesse | Caen, France | — |
| Centre Leon Berard | Lyon, France | — |
+ 21 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03869190