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Study identifier: NCT03810794 Synced from ClinicalTrials.gov · July 30, 2026
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Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease

Condition: Alzheimer Disease · Cognitive Impairment  ·  Sponsor: Jian Pei,MD

PhaseNA
Planned participants180
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersYes

About this study

The objective of this proposed study is to evaluate the effect and safety of acupuncture combined therapy on cognitive function, daily living ability and quality of life of Alzheimer's disease by using the international dementia certification scale. In this 12-week, assessor-blind, a Multi-center randomized, controlled study of acupuncture as additional treatment with Donepezil, a total of 180 patients with Alzheimer's disease will be recruited. The patients will be randomly assigned to acupuncture combined with Donepezil (n =90) or Donepezil treatment (n =90). (36 sessions, 3 sessions a week). Changes in the cognition over time measured using ADAS-cog is the primary outcome. MMSE, ADCS-ADL and QOL-AD are the secondary outcomes. The study will be conducted at LongHua Hospital Shanghai University of Traditional Chinese Medicine, Huashan Hospital Fudan University, and Mental Health Center Shanghai Jiao Tong University School of Medicine.

This description comes directly from the study's public registry record.

Talk to the study team

Jian Pei, Doctor  ·  00862164385700  ·  jianpei99@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (3)

LongHua Hospital Shanghai University of Traditional Chinese MedicineShanghai, Shanghai Municipality, ChinaRecruiting
Shanghai Mental Center, Shanghai Jiaotong University of Medicial SchoolShanghai, Shanghai Municipality, ChinaRecruiting
Huashan Hospital Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT03810794