Condition: Bladder Urothelial Carcinoma · Muscle Invasive Bladder Carcinoma · Stage II Bladder Cancer AJCC v8 · Sponsor: National Cancer Institute (NCI)
This phase III trial studies how well chemotherapy and radiation therapy work with or without atezolizumab in treating patients with localized muscle invasive bladder cancer. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Chemotherapy drugs, such as gemcitabine, cisplatin, fluorouracil and mitomycin-C, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving chemotherapy with radiation therapy may kill more tumor cells. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving atezolizumab with radiation therapy and chemotherapy may work better in treating patients with localized muscle invasive bladder cancer compared to radiation therapy and chemotherapy without atezolizumab.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| Mayo Clinic Hospital in Arizona | Phoenix, Arizona, United States | — |
| Mayo Clinic in Arizona | Scottsdale, Arizona, United States | — |
| Banner University Medical Center - Tucson | Tucson, Arizona, United States | — |
| University of Arizona Cancer Center-North Campus | Tucson, Arizona, United States | — |
| Sutter Auburn Faith Hospital | Auburn, California, United States | — |
| Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn, California, United States | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley, California, United States | — |
| Mercy Cancer Center - Carmichael | Carmichael, California, United States | — |
| Mercy San Juan Medical Center | Carmichael, California, United States | — |
| Mercy Cancer Center - Elk Grove | Elk Grove, California, United States | — |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | — |
| Los Angeles General Medical Center | Los Angeles, California, United States | — |
+ 354 more locations — full list on the registry record.
Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.
We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.