Condition: Stage III Non-small-cell Lung Cancer · Stage IV Non-small Cell Lung Cancer · Radiotherapy Side Effect · Sponsor: Danish Lung Cancer Group
The options for patients with locally advanced non-small cell lung cancer (NSCLC) who are not candidates for a standard definitive chemoradiotherapy regime are meagre. These are patients who are not fit for a chemoradiotherapy schedule of 66 Gy in 2 Gy fractions due to either tumour extent, resulting in excessive dose to the healthy tissue in the thorax, or with performance status not supporting seven weeks of intensive treatment. The aim is to study the efficiency as well as the safety of a new treatment option of heterogeneously hypofractionated radiotherapy for patients with locally advanced NSCLC who are not candidates for standard, high-dose chemoradiotherapy, either due to excessive irradiation of normal tissue (defined as category A patients) or due to fragility of the patient (category B patients).
This description comes directly from the study's public registry record.
Azza A Khalil, MD, PhD · +4578462556 · azzakhal@rm.dk
Marianne M Knap, MD, PhD · +4578462556 · mariknap@rm.dk
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| Aarhus University Hospital | Aarhus, Denmark | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03742687