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A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis
Condition: Juvenile Idiopathic Arthritis (JIA) · Sponsor: AbbVie
About this study
This is a study to evaluate pharmacokinetics, safety and tolerability of upadacitinib in pediatric participants with polyarticular course juvenile idiopathic arthritis. This study consists of three parts: Part 1 is multiple-cohort study that consists of two sequential multiple dose groups. Participants benefiting from the study drug with no ongoing adverse events of special interest or serious adverse events will have option to enroll in Part 2. Part 2 is open-label, long term extension study to evaluate safety and tolerability. Part 3 is an additional safety cohort to evaluate long-term safety and tolerability. Participants \<18 years of age who are ongoing in Parts 2 and 3 will participate in an 104 week open-label extension of the study in Part 4.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (35)
| Ann & Robert H. Lurie Children's Hospital of Chicago /ID# 211162 | Chicago, Illinois, United States | — |
| Duplicate_University of Louisville /ID# 202896 | Louisville, Kentucky, United States | — |
| Boston Children's Hospital /ID# 202993 | Boston, Massachusetts, United States | — |
| Cincinnati Childrens Hospital Medical Center /ID# 209697 | Cincinnati, Ohio, United States | — |
| Randall Children's Hospital /ID# 213609 | Portland, Oregon, United States | — |
| The Children's Hospital of Philadelphia /ID# 209617 | Philadelphia, Pennsylvania, United States | — |
| Children's Hospital of Pittsburgh of UPMC /ID# 202994 | Pittsburgh, Pennsylvania, United States | — |
| Seattle Children's Hospital /ID# 203003 | Seattle, Washington, United States | — |
| Alberta Children's Hospital /ID# 251738 | Calgary, Alberta, Canada | — |
| British Columbia Children and Women's Hospital and Health Centre /ID# 251736 | Vancouver, British Columbia, Canada | — |
| Duplicate_McGill University Health Centre /ID# 251252 | Montreal, Quebec, Canada | — |
| Asklepios Klinik Sankt Augustin /ID# 203264 | Sankt Augustin, North Rhine-Westphalia, Germany | — |
+ 23 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03725007