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Study identifier: NCT03668041 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

National Adaptive Trial for PTSD Related Insomnia

Condition: Insomnia  ·  Sponsor: VA Office of Research and Development

PhasePhase 3
Planned participants673
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone or eszopiclone can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficulty sleeping, poor concentration, irritability, anger, and emotional withdrawal. Insomnia is a disorder that can make it hard to fall sleep, stay asleep or cause a person to wake up too early and not be able to fall back to sleep.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (35)

Birmingham VA Medical Center, Birmingham, ALBirmingham, Alabama, United States
Tuscaloosa VA Medical Center, Tuscaloosa, ALTuscaloosa, Alabama, United States
Phoenix VA Health Care System, Phoenix, AZPhoenix, Arizona, United States
VA Loma Linda Healthcare System, Loma Linda, CALoma Linda, California, United States
VA Long Beach Healthcare System, Long Beach, CALong Beach, California, United States
VA Palo Alto Health Care System, Palo Alto, CAPalo Alto, California, United States
VA San Diego Healthcare System, San Diego, CASan Diego, California, United States
San Francisco VA Medical Center, San Francisco, CASan Francisco, California, United States
VA Connecticut Healthcare System West Haven Campus, West Haven, CTWest Haven, Connecticut, United States
CERC (VISN1, West Haven, CT)West Haven, Connecticut, United States
Bay Pines VA Healthcare System, Pay Pines, FLBay Pines, Florida, United States
Atlanta VA Medical and Rehab Center, Decatur, GADecatur, Georgia, United States

+ 23 more locations — full list on the registry record.

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