EICHOR
● Active Not Recruiting
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
Condition: Colorectal Neoplasms · Carcinoma, Non-Small-Cell Lung · Exocrine Pancreatic Cancer · Sponsor: Seagen, a wholly owned subsidiary of Pfizer
About this study
This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors and what side effects (unwanted effects) may occur. There are seven parts to this study. * In Part A, participants will receive tisotumab vedotin every 3 weeks (3-week cycles). * In Part B, participants will receive tisotumab vedotin on Days 1, 8, and 15 every 4-week cycle. * In Part C, participants will receive tisotumab vedotin on Days 1 and 15 of every 4-week cycle. * In Part D, participants will be given treatment on Day 1 of every 3-week cycle. * Participants in Part D will get tisotumab vedotin with either: * Pembrolizumab or, * Pembrolizumab and carboplatin, or * Pembrolizumab and cisplatin * In Part E, participants will receive tisotumab vedotin on Days 1 and 15 of every 4-week cycle. * In Part F, participants will receive tisotumab vedotin on Days 1, 15, and 29 of every 6-week cycle. Participants in Part F will get tisotumab vedotin with pembrolizumab. * In Part G, participants will receive tisotumab vedotin on Days 1, 15, and 29 of every 6-week cycle. Participants in Part G will get tisotumab vedotin with pembrolizumab and carboplatin. The objectives of the study have been achieved. Therefore, the study will transition to a long-term extension phase (LTEP). * In LTEP, participants still receiving clinical benefit based on the investigator's assessment and remaining on treatment may continue receiving treatme…
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (175)
| UCSD Medical Center - Encinitas | Encinitas, California, United States | — |
| UC San Diego Medical Center - La Jolla (Jacobs Medical Center / Thornton Pavilion) | La Jolla, California, United States | — |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | — |
| UCSD Koman Family Outpatient Pavilion | La Jolla, California, United States | — |
| UC San Diego/Moores Cancer Center | La Jolla, California, United States | — |
| UCSD Shiley Eye Institute | La Jolla, California, United States | — |
| University of California Davis Medical Center | Sacramento, California, United States | — |
| University of California, Davis Comprehensive Cancer Center | Sacramento, California, United States | — |
| UC San Diego Medical Center- Hillcrest | San Diego, California, United States | — |
| UC San Diego Health - Rancho Bernardo | San Diego, California, United States | — |
| Stanford Cancer Center South Bay | San Jose, California, United States | — |
| UCSD Medical Center - Vista | Vista, California, United States | — |
+ 163 more locations — full list on the registry record.
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