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Study identifier: NCT03449238 Synced from ClinicalTrials.gov · July 30, 2026
● Recruiting

Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

Condition: Metastatic Breast Cancer · Brain Metastases  ·  Sponsor: Weill Medical College of Cornell University

PhasePhase 1/Phase 2
Planned participants41
Who can joinFemale, 19 Years to 90 Years
Healthy volunteersNo

About this study

Patients with metastatic breast cancer with at least 2 brain metastases will receive pembrolizumab every 3 weeks. Patients will undergo stereotactic radiosurgery (SRS) to one of the brain lesions. Pembrolizumab infusion will be given on Day 4 (+/-1) after SRS treatment at the standard dose of 200mg IV over 30 minutes and repeated every 3 weeks until disease progression or unacceptable toxicity.

This description comes directly from the study's public registry record.

Talk to the study team

Fabiana Gregucci, M.D.  ·  646-962-3110  ·  fgr4002@med.cornell.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Weill Cornell MedicineNew York, New York, United StatesRecruiting
Brooklyn Methodist Hospital - NewYork PresbyterianNew York, New York, United StatesRecruiting
New York Presbyterian Hospital - QueensNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03449238