Condition: Primary Immune Deficiency Disorder · Sponsor: University of Zurich
The pathophysiology of primary immunodeficiencies (PID), which encompass a broad range of different diseases with susceptibility to infection and/or a deregulated inflammatory response, is poorly understood. Available treatments are often not specific for a distinct target and might be associated with side effects. To elucidate pathophysiology of different PIDs, stool, urine, blood, tissue biopsies and/or bone marrow will be collected and analysed for anti-microbial activity and inflammatory response. In a second step, targeted treatment for different PIDs might be developed preclinically and ex vivo according to underlying pathophysiology.
This description comes directly from the study's public registry record.
Janine Reichenbach, Prof. Dr. · +41442667311 · janine.reichenbach@kispi.uzh.ch
Ulrich Siler, PD Dr. · +41442667311 · ulrich.siler@kispi.uzh.ch
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| University Children's Hospital Zurich | Zurich, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03422614