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Study identifier: NCT03390504 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

Condition: Urothelial Cancer  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants629
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-\[L\]1) agent (cohort 1) or 1 prior treatment not containing an anti-PD-(L) 1 agent (cohort 2).

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (345)

Alaska Urological Institute dba Alaska Clinical Research CenterAnchorage, Alaska, United States
University of Calif Davis Medical CenterSacramento, California, United States
St. Helena Hospital - Martin-O'Neil Cancer CenterSt. Helena, California, United States
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United States
University of Miami Sylvester Cancer CenterMiami, Florida, United States
Mid Florida Hematology OncologyOrange, Florida, United States
Piedmont Cancer InstituteAtlanta, Georgia, United States
Rush UniversityChicago, Illinois, United States
Edward Hines Jr V A HospitalHines, Illinois, United States
Norton Cancer InstituteLouisville, Kentucky, United States
Maryland Oncology Hematology, PALanham, Maryland, United States
University of Michigan Health SystemAnn Arbor, Michigan, United States

+ 333 more locations — full list on the registry record.

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