EichorEICHOR
Study identifier: NCT03386539 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score

Condition: Pediatric Heart Transplantation · Immunosuppression · Chronic Kidney Diseases  ·  Sponsor: Boston Children's Hospital

PhasePhase 3
Planned participants211
Who can joinAll sexes, N/A to 21 Years
Healthy volunteersNo

About this study

The TEAMMATE Trial will enroll 210 pediatric heart transplant patients from 25 centers at 6 months post-transplant and follow each patient for 2.5 years. Half of the participants will receive everolimus and low-dose tacrolimus and the other half will receive tacrolimus and mycophenolate mofetil. The trial will determine which treatment is better at reducing the cumulative risk of coronary artery vasculopathy, chronic kidney disease and biopsy proven-acute cellular rejection without an increase in graft loss due to all causes (e.g. infection, PTLD, antibody mediated rejection).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (25)

Children's of AlabamaBirmingham, Alabama, United States
Phoenix Children's HospitalPhoenix, Arizona, United States
Loma Linda UniversityLoma Linda, California, United States
Children's Hospital Los AngelesLos Angeles, California, United States
UCLA Mattel Children's HospitalLos Angeles, California, United States
Stanford UniversityPalo Alto, California, United States
Children's Hospital ColoradoAurora, Colorado, United States
Children's National Medical CenterWashington D.C., District of Columbia, United States
University of Florida Congenital Heart CenterGainesville, Florida, United States
Joe DiMaggio Children's HospitalHollywood, Florida, United States
Children's Healthcare of Atlanta EmoryAtlanta, Georgia, United States
Lurie Children's HospitalChicago, Illinois, United States

+ 13 more locations — full list on the registry record.

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