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Study identifier: NCT03379909 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer

Condition: Superficial Bladder Cancer · Bladder Cancer  ·  Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

PhasePhase 2
Planned participants49
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A multi-center, open-label, phase II clinical study of metformin in up to evaluable 49 patients with low-grade NMIBC with the aim to determine the overall response to administration of oral metformin for 3 months in a index papillary NMIBC tumour.

This description comes directly from the study's public registry record.

Talk to the study team

M. J. Remmelink, MD  ·  0204441376  ·  m.j.remmelink@amsterdamumc.nl

J. W. Wilmink, MD, PhD  ·  0205665983  ·  j.w.wilmink@amsterdamumc.nl

Always discuss trial participation with your own doctor first.

Locations (3)

RadboudUMCNijmegen, Gelderland, NetherlandsNot Yet Recruiting
Sint Franciscus GasthuisRotterdam, South Holland, NetherlandsNot Yet Recruiting
Academic Medical CenterAmsterdam, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT03379909