EichorEICHOR
Study identifier: NCT03358472 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

Condition: Head and Neck Cancer  ·  Sponsor: Incyte Corporation

PhasePhase 3
Planned participants89
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study was to evaluate the efficacy and safety of pembrolizumab plus epacadostat, pembrolizumab monotherapy, and the EXTREME regimen (cetuximab + cisplatin or carboplatin + 5-fluorouracil) as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (73)

Pacific Cancer Medical CenterAnaheim, California, United States
UC Davis Comprehensive Cancer CenterSacramento, California, United States
St. Joseph Heritage HealthcareSanta Rosa, California, United States
University of Colorado Cancer CenterAurora, Colorado, United States
Yale Cancer CenterNew Haven, Connecticut, United States
Northwest Georgia Oncology Centers PCDouglasville, Georgia, United States
U of Kansas Cancer CenterWestwood, Kansas, United States
Baptist HealthLouisville, Kentucky, United States
St. Vincent Healthcare Cancer CtrBillings, Montana, United States
New Mexico Cancer Care AllianceAlbuquerque, New Mexico, United States
Oklahoma Cancer Specialists and ResearchTulsa, Oklahoma, United States
Providence Portland Med CenterPortland, Oregon, United States

+ 61 more locations — full list on the registry record.

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