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Study identifier: NCT03328884 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients

Condition: Breast Cancer Metastatic  ·  Sponsor: MedSIR

PhasePhase 2
Planned participants55
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Multicenter open-label, phase II trial, to evaluate the efficacy and safety of nal-IRI in patients with HER2-negative breast cancer, who have documented Central Nervous System (CNS) progression following Whole Brain Radio Therapy (WBRT), Stereotactic Radiosurgery (SRS) and/or surgery, as determined by the Response Assessment in Neuro-Oncology Brain Metastases (RANO-BM) criteria.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (16)

ICOBadalona, Spain
IOB Institute of Oncology - Quirón BarcelonaBarcelona, Spain
Hospital Universitario Virgen de Las NievesGranada, Spain
Hospital Universitario Clinico San CecilioGranada, Spain
H. Ruber Juan BravoMadrid, Spain
Hospital Clínico San CarlosMadrid, Spain
Hospital Doce de OctubreMadrid, Spain
Hospital Universitario Ramón y CajalMadrid, Spain
MD Anderson MadridMadrid, Spain
Hospital Clínico Virgen de la VictoriaMálaga, Spain
Hospital Universitari Son EspasesPalma de Mallorca, Spain
Son LlatzerPalma de Mallorca, Spain

+ 4 more locations — full list on the registry record.

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