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Study identifier: NCT03272698 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

Condition: Treatment Resistant Depression · Ketamine  ·  Sponsor: University of Saskatchewan

PhasePhase 4
Planned participants62
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To determine if an high intensity ketamine with ECT rescue (HIKER) approach for treatment resistant depression will: 1) reduce patient suffering by hastening disease remission, 2) have fewer side effects, 3) reduce the need for ECT, and 4) be preferred by most patients. Half of participants will be randomized to the HIKER arm and receive high intensity ketamine treatment for eight consecutive days, and the other half will be assigned to the ECT with ketamine anesthesia (EAST) arm and receive 8 ECT treatments (2-3 treatment/week)

This description comes directly from the study's public registry record.

Talk to the study team

Una Goncin  ·  3066551183  ·  ung039@usask.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Royal University HospitalSaskatoon, Saskatchewan, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03272698