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Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma
Condition: Anaplastic Astrocytoma · Anaplastic Oligoastrocytoma · Anaplastic Oligodendroglioma · Sponsor: NRG Oncology
About this study
This randomized phase II clinical trial studies the side effects and how well proton beam or intensity-modulated radiation therapy works in preserving brain function in patients with IDH mutant grade II or III glioma. Proton beam radiation therapy uses tiny charged particles to deliver radiation directly to the tumor and may cause less damage to normal tissue. Intensity-modulated or photon beam radiation therapy uses high-energy x-ray beams shaped to treat the tumor and may also cause less damage to normal tissue. It is not yet known if proton beam radiation therapy is more effective than photon-based beam intensity-modulated radiation therapy in treating patients with glioma.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (34)
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | — |
| Boca Raton Regional Hospital | Boca Raton, Florida, United States | — |
| Miami Cancer Institute | Miami, Florida, United States | — |
| Emory Proton Therapy Center | Atlanta, Georgia, United States | — |
| Emory University Hospital Midtown | Atlanta, Georgia, United States | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta, Georgia, United States | — |
| Northwestern University | Chicago, Illinois, United States | — |
| Northwestern Medicine Cancer Center Delnor | Geneva, Illinois, United States | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville, Illinois, United States | — |
| University of Kansas Cancer Center | Kansas City, Kansas, United States | — |
| University of Kansas Cancer Center-Overland Park | Overland Park, Kansas, United States | — |
| University of Kansas Hospital-Westwood Cancer Center | Westwood, Kansas, United States | — |
+ 22 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03180502