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Study identifier: NCT03108495 Synced from ClinicalTrials.gov · August 02, 2026
● Terminated

Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma

Condition: Cervical Carcinoma  ·  Sponsor: Iovance Biotherapeutics, Inc.

PhasePhase 2
Planned participants210
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Prospective, multicenter, multiple cohort, open label, interventional study evaluating adoptive cell therapy (ACT) with autologous tumor infiltrating lymphocytes (TIL) infusion (LN-145), with or without pembrolizumab, followed by IL-2 after a non-myeloablative lymphodepletion (NMA-LD) preparative regimen for the treatment of participants with recurrent, metastatic, or persistent cervical carcinoma.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (43)

St. Joseph's Hospital and Medical Center Center For Women's HealthPhoenix, Arizona, United States
University of Southern CaliforniaLos Angeles, California, United States
University of California San DiegoSan Diego, California, United States
Sylvester Comprehensive Cancer CenterMiami, Florida, United States
University of Florida Health Cancer CenterOrlando, Florida, United States
University of South Florida H. Lee Moffitt Cancer Center and Research InstituteTampa, Florida, United States
Augusta UniversityAugusta, Georgia, United States
University of ChicagoChicago, Illinois, United States
James Graham Brown Cancer CenterLouisville, Kentucky, United States
LSU Health Sciences CenterNew Orleans, Louisiana, United States
The Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland, United States
Dana Farber Cancer InstituteBoston, Massachusetts, United States

+ 31 more locations — full list on the registry record.

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