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Study identifier: NCT03104374 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

A Study Comparing Upadacitinib (ABT-494) to Placebo in Participants With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologic Disease Modifying Anti-Rheumatic Drug

Condition: Psoriatic Arthritis  ·  Sponsor: AbbVie

PhasePhase 3
Planned participants642
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 3 multicenter study that included two periods. Period 1 was designed to compare the safety, tolerability, and efficacy of upadacitinib 15 mg once daily (QD) and 30 mg QD versus placebo in participants with moderately to severely active Psoriatic Arthritis (PsA) who had an inadequate response to Biological Disease Modifying Anti-Rheumatic Drug (bDMARDs). Period 2 evaluated the safety, tolerability and efficacy of upadacitinib 15 mg QD and 30 mg QD in subjects with PsA who completed Period 1.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (165)

Alabama Medical Group, PC /ID# 159836Mobile, Alabama, United States
Arizona Arthritis & Rheumatology Research, PLLC /ID# 160047Mesa, Arizona, United States
Sun Valley Arthritis Center Ltd. /ID# 161203Peoria, Arizona, United States
Duplicate_AZ Arthritis and Rheumotology Research, PLLC /ID# 160006Phoenix, Arizona, United States
Osteoporosis Medical Center /ID# 161411Beverly Hills, California, United States
Covina Arthritis Clinic /ID# 159919Covina, California, United States
Triwest Research Associates /ID# 159915El Cajon, California, United States
Duplicate_Providence Medical Foundation /ID# 160005Fullerton, California, United States
C.V. Mehta MD, Med Corporation /ID# 161192Hemet, California, United States
Care Access Research, Huntington Beach /ID# 160049Huntington Beach, California, United States
Purushotham & Akther Kotha MD, Inc /ID# 159834La Mesa, California, United States
Stanford University School of Med /ID# 161402Stanford, California, United States

+ 153 more locations — full list on the registry record.

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