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Study identifier: NCT03041311 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC

Condition: Small Cell Lung Cancer  ·  Sponsor: G1 Therapeutics, Inc.

PhasePhase 2
Planned participants107
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This was a study to investigate the potential clinical benefit of trilaciclib (G1T28) in preserving the bone marrow and the immune system, and enhancing antitumor efficacy when administered with carboplatin, etoposide, and atezolizumab (E/P/A) therapy in first line treatment for patients with newly diagnosed extensive-stage SCLC. The study was a randomized, double-blinded, placebo-controlled design. Approximately, 100 patients were randomized to trilaciclib + E/P/A or placebo + E/P/A in the study.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (45)

Beverly Hills Cancer CenterBeverly Hills, California, United States
St. Jude Heritage HealthcareFullerton, California, United States
Loma Linda UniversityLoma Linda, California, United States
UCLA Medical Center - Santa Monica Hematology And OncologySanta Monica, California, United States
Redwood Regional Medical Group (RRMG) - Fountain GroveSanta Rosa, California, United States
Singing River Health SystemWhittier, California, United States
Piedmont Cancer InstituteAtlanta, Georgia, United States
Northside Hospital - Georgia Cancer SpecialistsAtlanta, Georgia, United States
Joliet Oncology-Hematology AssociatesJoliet, Illinois, United States
Horizon Oncology CenterLafayette, Indiana, United States
Ochsner Clinic FoundationNew Orleans, Louisiana, United States
St. Louis Cancer Care, LLP, North CountyBridgeton, Missouri, United States

+ 33 more locations — full list on the registry record.

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