EICHOR
● Completed
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
Condition: Osteomyelitis · Diabetes · Amputation · Sponsor: VA Office of Research and Development
About this study
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to other antibiotics is effective in treating osteomyelitis in both diabetics and non-diabetics. However, because few diabetics with osteomyelitis have been studied, there is no definite proof that it is better than the usual treatments for diabetic patients. If this study finds that adding rifampin to the usual antibiotics prescribed for osteomyelitis reduces the risk for amputations, doctors will be able to more effectively treat many Veteran patients with this serious infection. Improving treatment outcomes is an important healthcare goal of the VA.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
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Locations (30)
| Phoenix VA Health Care System, Phoenix, AZ | Phoenix, Arizona, United States | — |
| VA Loma Linda Healthcare System, Loma Linda, CA | Loma Linda, California, United States | — |
| VA Long Beach Healthcare System, Long Beach, CA | Long Beach, California, United States | — |
| VA Palo Alto Health Care System, Palo Alto, CA | Palo Alto, California, United States | — |
| VA Northern California Health Care System, Mather, CA | Sacramento, California, United States | — |
| VA Greater Los Angeles Healthcare System, West Los Angeles, CA | West Los Angeles, California, United States | — |
| Rocky Mountain Regional VA Medical Center, Aurora, CO | Aurora, Colorado, United States | — |
| Washington DC VA Medical Center, Washington, DC | Washington D.C., District of Columbia, United States | — |
| Bay Pines VA Healthcare System, Pay Pines, FL | Bay Pines, Florida, United States | — |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Gainesville, Florida, United States | — |
| Miami VA Healthcare System, Miami, FL | Miami, Florida, United States | — |
| James A. Haley Veterans' Hospital, Tampa, FL | Tampa, Florida, United States | — |
+ 18 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03012529