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Study identifier: NCT02864992 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)

Condition: Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification · Lung Adenocarcinoma Stage IIIB/IV  ·  Sponsor: EMD Serono Research & Development Institute, Inc.

PhasePhase 2
Planned participants337
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study looked at how effective the study drug (tepotinib) was at stopping the growth and spread of lung cancer. This study also measures a number of other things including safety of the study drug and the side effects, how body processes the study drug, or how the study drug affects your quality of life. The study also has an optional pharmacogenetic research part. Pharmacogenetic research is an important way to try to understand the role of genetics in human disease and how genes impact the effectiveness of drugs, because differences in genes can change the way a person responds to a particular drug.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (176)

City of Hope Cancer CenterDuarte, California, United States
California Cancer Associates for Research & Excellence, Inc.Encinitas, California, United States
St. Joseph HospitalOrange, California, United States
Torrance Health AssociationRedondo Beach, California, United States
St Joseph Heritage HealthcareSanta Rosa, California, United States
Rocky Mountain Cancer Centers, LLPDenver, Colorado, United States
Holy Cross Hospital Inc.Fort Lauderdale, Florida, United States
H. Lee Moffitt Cancer Center and Research Institute, IncTampa, Florida, United States
University Cancer & Blood Center, LLCAthens, Georgia, United States
Winship Cancer InstituteAtlanta, Georgia, United States
University of Chicago Medical CenterChicago, Illinois, United States
Ingalls HospitalHarvey, Illinois, United States

+ 164 more locations — full list on the registry record.

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