Study identifier: NCT02785952 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Condition: Recurrent Squamous Cell Lung Carcinoma · Stage IV Squamous Cell Lung Carcinoma AJCC v7  ·  Sponsor: SWOG Cancer Research Network

PhasePhase 3
Planned participants275
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized phase III trial compares nivolumab with ipilimumab and nivolumab alone in treating patients with stage IV squamous cell lung cancer that has come back after previous treatment. This is a "non-match" sub-study that includes all screened patients not eligible for a biomarker-driven sub-study. Monoclonal antibodies, such as nivolumab and ipilimumab, may be able to shrink tumors. It is not yet known whether nivolumab works better with or without ipilimumab in treating patients with squamous cell lung cancer.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (1207)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United States
Anchorage Associates in Radiation MedicineAnchorage, Alaska, United States
Anchorage Radiation Therapy CenterAnchorage, Alaska, United States
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United States
Alaska Oncology and Hematology LLCAnchorage, Alaska, United States
Alaska Regional HospitalAnchorage, Alaska, United States
Alaska Women's Cancer CareAnchorage, Alaska, United States
Anchorage Oncology CentreAnchorage, Alaska, United States
Katmai Oncology GroupAnchorage, Alaska, United States
Providence Alaska Medical CenterAnchorage, Alaska, United States
Fairbanks Memorial HospitalFairbanks, Alaska, United States
University of Arizona Cancer Center-North CampusTucson, Arizona, United States

+ 1195 more locations — full list on the registry record.

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