EICHOR
● Completed
National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer · Carcinoma, Squamous Cell · Adenocarcinoma · Sponsor: University of Birmingham
About this study
The trial consists of a series of parallel multi-centre single arm phase II trial arms, each testing an experimental targeted drug in a population stratified by multiple pre-specified actionable target putative biomarkers. The primary objective is to evaluate whether there is a signal of activity in each drug-(putative)biomarker cohort separately. A Bayesian adaptive design is adopted to achieve this objective and statistical details are given in the Protocol.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (25)
| Aberdeen Royal Infirmary | Aberdeen, United Kingdom | — |
| Belfast City Hospital, Belfast Health and Social Care Trust | Belfast, United Kingdom | — |
| Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust | Birmingham, United Kingdom | — |
| Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust | Birmingham, United Kingdom | — |
| University Hospitals Bristol NHS Foundation Trust | Bristol, United Kingdom | — |
| Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust | Cambridge, United Kingdom | — |
| Velindre Cancer Centre, Velindre NHS Trust | Cardiff, United Kingdom | — |
| Colchester General Hospital | Colchester, United Kingdom | — |
| Edinburgh Cancer Centre, Western General Hospital | Edinburgh, United Kingdom | — |
| Royal Devon and Exeter Hospital | Exeter, United Kingdom | — |
| Beatson West of Scotland Cancer Centre | Glasgow, United Kingdom | — |
| St. James' University Hospital, Leeds Teaching Hospital NHS Trust | Leeds, United Kingdom | — |
+ 13 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT02664935