EichorEICHOR
Study identifier: NCT02492711 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast Cancer

Condition: HER-2 Positive Breast Cancer · Metastatic Neoplasm  ·  Sponsor: MacroGenics

PhasePhase 3
Planned participants624
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine whether patients with metastatic breast cancer treated with margetuximab plus chemotherapy have longer progression free survival (PFS) and overall survival (OS) than patients treated with trastuzumab plus chemotherapy. A non-randomized sub-study cohort of approximately 88 patients will be enrolled to evaluate the safety of a reduced margetuximab infusion rate in patients receiving margetuximab either as monotherapy or in combination with chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (167)

Ironwood Cancer & Research CenterChandler, Arizona, United States
Banner MD Anderson Cancer CenterGilbert, Arizona, United States
Western Regional Medical Center, Inc.Goodyear, Arizona, United States
East Valley Hematology And OncologyBurbank, California, United States
UCLA Hematology Oncology Santa MonicaLos Angeles, California, United States
UC Davis Comprehensive Cancer CenterSacramento, California, United States
Sharp Memorial HospitalSan Diego, California, United States
University of California, San Francisco Helen Diller Family Comprehensive Cancer CenterSan Francisco, California, United States
Kaiser Permenente Medical CenterVallejo, California, United States
Poudre Valley Health Care, Inc.Fort Collins, Colorado, United States
MedStar Washington Hospital CenterWashington D.C., District of Columbia, United States
Florida Cancer SpecialistsFort Myers, Florida, United States

+ 155 more locations — full list on the registry record.

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