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Study identifier: NCT02486718 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Condition: Non-Small Cell Lung Cancer  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants1280
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase III, global, multicenter, open-label, randomized study to compare the efficacy and safety of 16 cycles (1 cycle duration=21 days) of atezolizumab (MPDL3280A) treatment compared with best supportive care (BSC) in participants with Stage IB-Stage IIIA non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy, as measured by disease-free survival (DFS) as assessed by the investigator and overall survival (OS). Participants, after completing up to 4 cycles of adjuvant cisplatin-based chemotherapy, will be randomized in a 1:1 ratio to receive atezolizumab for 16 cycles or BSC.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (155)

Highlands Oncology GroupFayetteville, Arkansas, United States
California Cancer Associates for Research & Excellence, Inc.Encinitas, California, United States
Compassionate Cancer Care Medical Group, IncFountain Valley, California, United States
University of California Los AngelesLos Angeles, California, United States
Kaiser PermanenteVallejo, California, United States
Kaiser Permanente - Walnut CreekWalnut Creek, California, United States
Eastern Connecticut Hematology and Oncology AssociatesNorwich, Connecticut, United States
Lynn Cancer Institute - WestBoca Raton, Florida, United States
University of Miami School of Medicine - Sylvester at DeerfieldDeerfield Beach, Florida, United States
SCRI Florida Cancer Specialists NorthSt. Petersburg, Florida, United States
Lewis Hall Singletary Oncology CenterThomasville, Georgia, United States
University of Illinois at ChicagoChicago, Illinois, United States

+ 143 more locations — full list on the registry record.

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