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Study identifier: NCT02442375 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity

Condition: Head and Neck Neoplasms · Carcinoma, Squamous Cell  ·  Sponsor: Radboud University Medical Center

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The objective of the UPGRADE-RT trial is to investigate whether de-escalation of elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation sequelae and improved quality of life after treatment whilst the recurrence rate in electively irradiated lymph nodes should not be compromised. The full study protocol can be found here: https://doi.org/10.1200/jco-24-02194

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (5)

VU University Medical Center AmsterdamAmsterdam, Netherlands
Radiotherapiegroep, ArnhemArnhem, Netherlands
MAASTRO clinic, MaastrichtMaastricht, Netherlands
Radboud University Nijmegen Medical CenterNijmegen, Netherlands
University Medical Center UtrechtUtrecht, Netherlands

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