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Study identifier: NCT02152982 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Condition: Glioblastoma · Gliosarcoma  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 2/Phase 3
Planned participants447
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized phase II/III trial studies how well temozolomide and veliparib work compared to temozolomide alone in treating patients with newly diagnosed glioblastoma multiforme. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether temozolomide is more effective with or without veliparib in treating glioblastoma multiforme.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (391)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United States
Katmai Oncology GroupAnchorage, Alaska, United States
Providence Alaska Medical CenterAnchorage, Alaska, United States
Mayo Clinic in ArizonaScottsdale, Arizona, United States
Banner University Medical Center - TucsonTucson, Arizona, United States
University of Arkansas for Medical SciencesLittle Rock, Arkansas, United States
Kaiser Permanente-Deer Valley Medical CenterAntioch, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, California, United States
Mills-Peninsula Medical CenterBurlingame, California, United States
John Muir Medical Center-ConcordConcord, California, United States
Kaiser Permanente-FremontFremont, California, United States
Fresno Cancer CenterFresno, California, United States

+ 379 more locations — full list on the registry record.

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