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Study identifier: NCT01874353 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

Condition: Platinum Sensitive · BRCA Mutated · Relapsed Ovarian Cancer  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants327
Who can joinFemale, 18 Years to 130 Years
Healthy volunteersNo

About this study

A Phase III, randomised, double-blind, placebo-controlled, multi-centre study to assess the efficacy of olaparib maintenance monotherapy in relapsed high grade serous ovarian cancer (HGSOC) patients (including patients with primary peritoneal and / or fallopian tube cancer) or high grade endometrioid cancer with BRCA mutations (documented mutation in BRCA1 or BRCA2 that is predicted to be deleterious or suspected deleterious (known or predicted to be detrimental/lead to loss of function)) who have responded following platinum based chemotherapy.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (126)

University of Alabama at BirminghamBirmingham, Alabama, United States
Palo Alto Foundation Medical GroupSan Francisco, California, United States
University of ColoradoAurora, Colorado, United States
The Hospital of Central ConnecticutNew Britain, Connecticut, United States
Gynecologic Cancer CenterOrlando, Florida, United States
North Shore UniversityEvanston, Illinois, United States
Greater Baltimore Medical CenterBaltimore, Maryland, United States
Johns HopkinsBaltimore, Maryland, United States
Dana Farber Cancer InstituteBoston, Massachusetts, United States
Massachusetts General HospitalBoston, Massachusetts, United States
MD Anderson at Cooper Cancer CenterVoorhees Township, New Jersey, United States
Womens Cancer Care AssociatesAlbany, New York, United States

+ 114 more locations — full list on the registry record.

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