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Study identifier: NCT01740427 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)

Condition: Breast Neoplasms  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants666
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is designed to compare the clinical benefit following treatment with letrozole in combination with PD-0332991 versus letrozole in combination with placebo in postmenopausal women with ER(+)/HER2(-) advanced breast cancer who have not received prior systemic anti cancer therapies for their advanced/metastatic disease.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (305)

Southern California Permanente Medical GroupBellflower, California, United States
Beverly Hills Cancer CenterBeverly Hills, California, United States
St. Joseph Heritage HealthcareFullerton, California, United States
Los Angeles Hematology/Oncology Medical GroupGlendale, California, United States
UCLA Hematology/ Oncology- IrvineIrvine, California, United States
UCLA Hematology Oncology- Laguna HillsLaguna Hills, California, United States
Los Angeles Hematology/Oncology Medical GroupLos Angeles, California, United States
Southern California Permanente Medical GroupLos Angeles, California, United States
Translational Research ManagementLos Angeles, California, United States
Drug Management Only: UCLA West Medical Pharmacy, Attn: Steven L Wong, Pharm.D.Los Angeles, California, United States
UCLA West Medical Pharmacy, Attn: Steven L. WongLos Angeles, California, United States
UCLA West Medical Pharmacy: Drug Management OnlyLos Angeles, California, United States

+ 293 more locations — full list on the registry record.

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