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Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
Condition: Endometrial Adenocarcinoma · Endometrial Adenosquamous Carcinoma · Endometrial Clear Cell Adenocarcinoma · Sponsor: National Cancer Institute (NCI)
About this study
This randomized phase II trial studies paclitaxel, carboplatin, and bevacizumab or paclitaxel, carboplatin, and temsirolimus or ixabepilone, carboplatin, and bevacizumab to see how well they work in treating patients with stage III, stage IV, or recurrent endometrial cancer. Drugs used in chemotherapy, such as paclitaxel, carboplatin, and ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known which treatment regimen is most effective in treating patients with endometrial cancer.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (230)
| Saint Joseph's Hospital and Medical Center | Phoenix, Arizona, United States | — |
| Mayo Clinic in Arizona | Scottsdale, Arizona, United States | — |
| University of Arizona Cancer Center-North Campus | Tucson, Arizona, United States | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank, California, United States | — |
| John Muir Medical Center-Concord | Concord, California, United States | — |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | — |
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | — |
| Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View, California, United States | — |
| UC San Diego Medical Center - Hillcrest | San Diego, California, United States | — |
| San Diego VA Medical Center | San Diego, California, United States | — |
| UCSF Medical Center-Mount Zion | San Francisco, California, United States | — |
| John Muir Medical Center-Walnut Creek | Walnut Creek, California, United States | — |
+ 218 more locations — full list on the registry record.
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