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Study identifier: NCT00602641 Synced from ClinicalTrials.gov · August 04, 2026
● Active Not Recruiting

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Condition: Multiple Myeloma  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 3
Planned participants306
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized phase III trial studies melphalan and prednisone with thalidomide to see how well it works compared to melphalan and prednisone together with lenalidomide in treating patients with newly diagnosed multiple myeloma. Drugs used in chemotherapy, such as melphalan and prednisone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Thalidomide and lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. It is not yet known whether melphalan and prednisone are more effective when given together with thalidomide or lenalidomide in treating multiple myeloma.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (391)

Providence HospitalMobile, Alabama, United States
Mayo Clinic in ArizonaScottsdale, Arizona, United States
Sparks Regional Medical CenterFort Smith, Arkansas, United States
UC San Diego Moores Cancer CenterLa Jolla, California, United States
Fremont - Rideout Cancer CenterMarysville, California, United States
Memorial Medical CenterModesto, California, United States
University of California Davis Comprehensive Cancer CenterSacramento, California, United States
UC San Diego Medical Center - HillcrestSan Diego, California, United States
Kaiser Permanente-San Diego MissionSan Diego, California, United States
San Diego VA Medical CenterSan Diego, California, United States
Gene Upshaw Memorial Tahoe Forest Cancer CenterTruckee, California, United States
The Medical Center of AuroraAurora, Colorado, United States

+ 379 more locations — full list on the registry record.

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