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Study identifier: NCT00482092 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-resistant Moderate-to-severe Crohn's Disease

Condition: Crohn's Disease  ·  Sponsor: Mesoblast, Inc.

PhasePhase 3
Planned participants330
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Protocol 603 is enrolling subjects with moderate-to-severe Crohn's disease who are intolerant to, or have previously failed therapy with, at least one steroid and at least one immunosuppressant and a biologic monoclonal anti-body to tumor necrosis factor alpha. The protocol investigates the safety and efficacy of using PROCHYMAL® adult human stem cells to induce remission. PROCHYMAL is delivered through a vein in the arm four times over two weeks, for approximately an hour each time.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (56)

University of Southern California University HospitalLos Angeles, California, United States
University of California, San FranciscoSan Francisco, California, United States
Western States Clinical ResearchWheat Ridge, Colorado, United States
Clinical Research of West FloridaClearwater, Florida, United States
Borland-Groover ClinicJacksonville, Florida, United States
Shafran Gastroenterology CenterWinter Park, Florida, United States
Atlanta Gastroenterology AssociatesAtlanta, Georgia, United States
University of Chicago Medical CenterChicago, Illinois, United States
Carle Clinic AssociationUrbana, Illinois, United States
Indiana University Medical CenterIndianapolis, Indiana, United States
Cotton-O'Neil Clinical Research CenterTopeka, Kansas, United States
University of Kentucky HospitalLexington, Kentucky, United States

+ 44 more locations — full list on the registry record.

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