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Study identifier: NCT00309985 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer

Condition: Metastatic Hormone-sensitive Prostate Cancer  ·  Sponsor: ECOG-ACRIN Cancer Research Group

PhasePhase 3
Planned participants790
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen ablation therapy may stop the adrenal glands from making androgens. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether androgen-ablation therapy is more effective with or without docetaxel in treating metastatic prostate cancer. PURPOSE: This randomized phase III trial is studying androgen-ablation therapy and chemotherapy to see how well they work compared to androgen-ablation therapy alone in treating patients with metastatic prostate cancer.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (343)

Providence Cancer CenterAnchorage, Alaska, United States
Fairbanks Cancer Treatment Center at Fairbanks Memorial HospitalFairbanks, Alaska, United States
Mayo Clinic HospitalPhoenix, Arizona, United States
Mayo Clinic ScottsdaleScottsdale, Arizona, United States
Hembree Mercy Cancer Center at St. Edward Mercy Medical CenterFort Smith, Arkansas, United States
Arkansas Cancer Research Center at University of Arkansas for Medical SciencesLittle Rock, Arkansas, United States
Alta Bates Summit Comprehensive Cancer CenterBerkeley, California, United States
Peninsula Medical CenterBurlingame, California, United States
California Cancer Care, Incorporated - GreenbraeGreenbrae, California, United States
USC/Norris Comprehensive Cancer Center and HospitalLos Angeles, California, United States
Tibotec Therapeutics - Division of Ortho Biotech Products, LPMarysville, California, United States
Mather Veteran Affairs Medical CenterMather, California, United States

+ 331 more locations — full list on the registry record.

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