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Study identifier: NCT00114101 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Condition: DS Stage I Multiple Myeloma · DS Stage II Multiple Myeloma · DS Stage III Multiple Myeloma  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 3
Planned participants460
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This randomized phase III trial studies lenalidomide to see how well it works compared to a placebo in treating patients with multiple myeloma who are undergoing autologous stem cell transplant. Giving chemotherapy before a peripheral blood stem cell transplant helps kill any cancer cells that are in the body and helps make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy is then given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. Biological therapies, such as lenalidomide, may stimulate or suppress the immune system in different ways and stop cancer cells from growing. Giving lenalidomide after autologous stem cell transplant may be an effective treatment for multiple myeloma.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (140)

Mayo Clinic in ArizonaScottsdale, Arizona, United States
City of Hope Comprehensive Cancer CenterDuarte, California, United States
University of California Davis Comprehensive Cancer CenterSacramento, California, United States
UC San Diego Medical Center - HillcrestSan Diego, California, United States
UCSF Medical Center-Mount ZionSan Francisco, California, United States
The Medical Center of AuroraAurora, Colorado, United States
Boulder Community Foothills HospitalBoulder, Colorado, United States
Penrose-Saint Francis HealthcareColorado Springs, Colorado, United States
AdventHealth PorterDenver, Colorado, United States
Presbyterian - Saint Lukes Medical Center - Health OneDenver, Colorado, United States
Saint Joseph Hospital - Cancer Centers of ColoradoDenver, Colorado, United States
Rose Medical CenterDenver, Colorado, United States

+ 128 more locations — full list on the registry record.

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