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Study identifier: NCT07734116 Synced from ClinicalTrials.gov · July 29, 2026
● Not Yet Recruiting

A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma.

Condition: Pediatric Malignant Solid Tumor and Epithelioid Sarcoma  ·  Sponsor: Ono Pharmaceutical Co., Ltd.

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, uncontrolled Phase I/II study to evaluate the efficacy, safety, and pharmacokinetics of ONO-4538HSC in pediatric patients with malignant solid tumors and in patients with epithelioid sarcoma, and to evaluate the tolerability in pediatric patients. The objective of this study is to explore the tolerability, safety, efficacy, and pharmacokinetics of ONO-4538HSC in patients with pediatric malignant solid tumors. The other objective is to exploratively investigate the efficacy and safety of ONO-4538HSC in patients with epithelioid sarcoma.

This description comes directly from the study's public registry record.

Talk to the study team

North America Clinical Trial Support Desk  ·  +18665877745(Toll-Free)  ·  clinical_trial@ono-pharma.com

International Clinical Trial Support Desk  ·  +17162141777(Standard)  ·  clinical_trial@ono-pharma.com

Always discuss trial participation with your own doctor first.

Locations (3)

Yokohama City University HospitalYokohama, Kanagawa, Japan
Osaka International Cancer InstituteOsaka, Osaka, Japan
National Cancer Center HospitalChuo-ku, Tokyo, Japan

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Source record: clinicaltrials.gov/study/NCT07734116