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Study identifier: NCT07731542 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Vonoprazan Alone vs With Itopride for Functional Dyspepsia: The VIVA Trial

Condition: Functioanl Dyspepsia  ·  Sponsor: Asian Institute of Gastroenterology, India

PhaseNA
Planned participants192
Who can joinAll sexes, 20 Years to 50 Years
Healthy volunteersNo

About this study

The VIVA trial is a 12-week, randomized, interventional study comparing vonoprazan monotherapy versus vonoprazan plus itopride combination therapy in adults with functional dyspepsia (FD). FD is a common digestive disorder causing upper stomach discomfort, fullness after meals, and early satiety. The study aims to determine if adding itopride, a prokinetic that improves stomach emptying, to vonoprazan, a strong acid-suppressing drug, provides better symptom relief than vonoprazan alone. Participants will be randomly assigned to receive either treatment, and their symptoms, quality of life, and safety outcomes will be monitored throughout the study. The trial will help guide the best management strategy for FD by targeting both acid-related and motility-related symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Dr.Aniruddha Pratap singh, MD, DM  ·  9004093248  ·  Doc.aniruddha85@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Asian Institute of Gastroenterology/AIG HospitalsHyderabad, Telangana, IndiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07731542