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Study identifier: NCT07729319 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Effects of Intraoperative Heat and Moisture Exchange Systems During Thoracic Surgery: A Prospective Observational Cohort Study

Condition: Video Assisted Thoracic Surgery (VATS) · Postoperative Complications · Pulmonary Complications in Surgical Patients  ·  Sponsor: Marmara University

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

General anesthesia with endotracheal intubation bypasses the physiological warming and humidification functions of the upper airway, allowing cold and dry gases to reach the lower respiratory tract. This may impair mucociliary clearance, increase secretion viscosity, promote atelectasis, and contribute to postoperative pulmonary complications (PPCs). Patients undergoing thoracic surgery, particularly those requiring one-lung ventilation (OLV), are at increased risk for PPCs because of altered ventilation-perfusion matching, reduced functional residual capacity, and impaired secretion clearance. Although respiratory gas humidification is routinely used during anesthesia, evidence regarding the comparative clinical effects of active heated humidification (AHH) and passive heat and moisture exchangers (HMEs) during thoracic surgery remains limited. This prospective observational cohort study aims to evaluate the association between intraoperative respiratory gas humidification methods and postoperative pulmonary complications and perioperative clinical outcomes in adult patients undergoing elective video-assisted thoracoscopic surgery (VATS).

This description comes directly from the study's public registry record.

Talk to the study team

Nezaket Nur Arslan Kömür, MD  ·  +905392911654  ·  nnurarslan@gmail.com

Seniyye Ülgen Zengin, Associate Professor, MD  ·  +905057142443  ·  ulgen_t@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (1)

Marmara UniversityIstanbul, Istanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07729319