Condition: Acute Respiratory Distress Syndrome · Sponsor: Southeast University, China
China faces major challenges in the ECMO management of patients with moderate-to-severe ARDS, including substantial heterogeneity in clinical practice, low weaning success rates, and high complication rates. A key underlying reason is the lack of a standardized full-course management pathway that is applicable to real-world clinical practice in China. This study focuses on the construction and evidence-based evaluation of a precision full-course ECMO management pathway for patients with moderate-to-severe ARDS, aiming to address fragmented care processes and delayed quality improvement. The study includes three main components. First, multidisciplinary consensus and evidence-based findings will be integrated to develop a standardized management pathway covering the full chain of assessment, initiation, maintenance, weaning, and rehabilitation. Second, a nationwide multicenter real-world study with a before-and-after design will be conducted to systematically evaluate the clinical effectiveness of this pathway in reducing mortality and complications and improving patient outcomes. Third, a closed-loop dynamic optimization system based on "pathway-data-feedback-improvement" will be established. With the support of an intelligent data platform and multidisciplinary review mechanisms, the pathway will be continuously updated and refined. Through this study, a reproducible, traceable, and evaluable full-course ECMO management strategy is expected to be established. The study wil…
This description comes directly from the study's public registry record.
yingzi Huang, M.D. · 18271428804 · yz_huang@126.com
Always discuss trial participation with your own doctor first.
| Beijing Anzhen Hospital, Capital Medical University | Beijing, China | Recruiting |
| The Second Hospital of Jilin University | Changchun, China | Not Yet Recruiting |
| West China Tianfu Hospital, Sichuan University | Chengdu, China | Not Yet Recruiting |
| The First People's Hospital of Chenzhou | Chenzhou, China | Not Yet Recruiting |
| The Second Affiliated Hospital of Dalian Medical University | Dalian, China | Recruiting |
| Fuzhou University Affiliated Provincial Hospital | Fuzhou, China | Recruiting |
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou, China | Recruiting |
| Affiliated Hangzhou First People's Hospital of Westlake University School of Medicine | Hangzhou, China | Not Yet Recruiting |
| The Second Affiliated Hospital of Zhejiang University School of Medicine | Hangzhou, China | Recruiting |
| The First Affiliated Hospital of Harbin Medical University | Ha’erbin, China | Not Yet Recruiting |
| The Second Affiliated Hospital of Harbin Medical University | Ha’erbin, China | Recruiting |
| Huai'an First People's Hospital | Huai'an, China | Not Yet Recruiting |
+ 27 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07726953