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Study identifier: NCT07726511 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Hard Gum Chewing on Facial Soft Tissue Morphology

Condition: Face  ·  Sponsor: UConn Health

PhaseNA
Planned participants20
Who can joinAll sexes, 20 Years to 40 Years
Healthy volunteersNo

About this study

This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults. Twenty participants aged 20-40 years will undergo three-dimensional facial imaging (3dMD) at baseline (T0), after the 4-week chewing intervention (T1), and following a 4-5-week washout period (T2). Changes in facial soft-tissue morphology will be assessed using three-dimensional surface analysis, including heatmaps, regional surface displacement, and morphometric measurements. Secondary outcomes include self-reported muscle fatigue, soreness, adherence, and temporomandibular disorder (TMD) symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Flavio Uribe (Chair, Depto Orthodontics; UConn School of dental medic  ·  860-679-3170  ·  furibe@uchc.edu

Georgiana Defilio  ·  (860) 679-2550  ·  GEDEFILIO@uchc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UConn HealthFarmington, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07726511