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Study identifier: NCT07726420 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HEARTBEAT-TROP. Polyethylene Glycol Precipitation to Unmask Macrotroponin

Condition: Diagnoses Disease  ·  Sponsor: Technical University of Munich

PhaseNA
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Troponin elevation can, among others, be due to myocardial infarction, acute inflammation or structural heart disease. Formation of macrocomplexes against troponin is an underestimated cause for persistent troponin elevation. Polyethlylene glycol precipitation (PEG) can differentiate macrotroponin from real troponin elevation, but cut-off values for PEG have not been established. PEG is analyzed in patients with acute coronary syndrome undergoing invasive coronary angiography and compared to healthy marathon runners who have undergone cardiological pre-participation screening and have rested for 24 hours.

This description comes directly from the study's public registry record.

Talk to the study team

Simon Wernhart, MD, PhD  ·  +491751830099  ·  simon.wernhart@gmx.de

Sebastian Zenk, MD  ·  +49821227800  ·  sebastian.zenk@synlab.com

Always discuss trial participation with your own doctor first.

Locations (1)

Technical University MunichMunich, Bavaria, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT07726420