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Study identifier: NCT07722611 Synced from ClinicalTrials.gov · July 27, 2026
● Not Yet Recruiting

A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025)

Condition: Polycythemia Vera  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 2/Phase 3
Planned participants380
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat polycythemia vera (PV). People with PV may receive treatment to lower the number of red blood cells in the blood, but the usual treatments may not work for everyone. Researchers want to learn if a trial medicine called bomedemstat, also called MK-3543, can treat PV. In this study, researchers will compare bomedemstat to 2 usual treatments for PV. The goal of this study is to learn if more participants who take bomedemstat reach healthy blood cell counts and avoid major health problems from PV, compared to those who receive a usual treatment.

This description comes directly from the study's public registry record.

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Source record: clinicaltrials.gov/study/NCT07722611