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Study identifier: NCT07721766 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training

Condition: Healthy Volunteers · Muscle Hypertrophy · Glycolysis  ·  Sponsor: Technical University of Munich

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 39 Years
Healthy volunteersYes

About this study

The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training. Participants will undergo a specialized "vLapeak" test, which measures the maximal rate of lactate accumulation during a 10-second all-out cycling sprint, to determine their individual glycolytic power. Following this initial assessment, participants will complete eight weeks of standardized, twice-weekly resistance training focused on the lower body. The study aims to determine if individuals with higher initial vLapeak values experience greater increases in muscle size compared to those with lower values. This research may help explain why people respond differently to exercise and support the development of personalized training programs.

This description comes directly from the study's public registry record.

Talk to the study team

Henning Wackerhage, Prof. Dr.  ·  +49 89 289 24480  ·  henning.wackerhage@tum.de

Lara Becker  ·  lara.becker@tum.de

Always discuss trial participation with your own doctor first.

Locations (8)

University of Jyväskylä, Faculty of Sport and Health SciencesJyväskylä, Central Finland, FinlandRecruiting
Technical University of Munich, TUM School of Medicine and HealthMünchen, Bavaria, GermanyRecruiting
DLR Cologne, Department of Metabolism and Human PerformanceCologne, North Rhine-Westphalia, GermanyRecruiting
iST University of Applied SciencesDüsseldorf, North Rhine-Westphalia, GermanyRecruiting
TU Chemnitz, Sports Medicine and Exercise TherapyChemnitz, Saxony, GermanyRecruiting
Institute for Applied Training Science (IAT) LeipzigLeipzig, Saxony, GermanyRecruiting
University of Limerick, Department of Physical Education and Sport Sciences (PESS)Limerick, Limerick, IrelandRecruiting
Universidad Politécnica de Madrid, Facultad de Ciencias de la Actividad Física y del Deporte (INEF)Madrid, Madrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07721766