Condition: Multiple Sclerosis · Alzheimer Disease · Parkinson Disease · Sponsor: IRCCS San Raffaele
OCt.IN.N is a national, monocentric, prospective, observational cohort study evaluating the utility and applicability of Optical Coherence Tomography (OCT) in the diagnostic workup and longitudinal monitoring of neurological diseases. 840 patients with Central Nervous System neurological diseases (Multiple Sclerosis, Alzheimer's disease, Parkinson's disease, migraine/headache) and 210 age-matched healthy controls will undergo OCT examination at baseline and at 6, 12, 18, and 24 months of follow-up at IRCCS San Raffaele Hospital, Milan, Italy. OCT is a non-invasive, rapid, and reproducible technique that automatically measures the thickness of individual retinal layers. Retinal layer thicknesses and their longitudinal changes will be correlated with established clinical scales, neuroimaging, and biological markers used in routine neurological practice.
This description comes directly from the study's public registry record.
Federica Agosta, MD · 0226433051 · agosta.federica@hsr.it
Roberto Santangelo, MD
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| IRCCS Ospedale San Raffaele - Neurology and Neurophysiology Unit | Milan, Milano, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07720765