Condition: NSCLC (Advanced Non-small Cell Lung Cancer) · Sponsor: Multitude Therapeutics Inc.
This clinical trial consists of two parts: phase 2 and phase 3. The goal of phase 2 of this clinical trial is to compare which dose level of AMT-116 works better to treat advanced or metastatic non-squamous EGFR-Wildtype non-small cell lung cancer (NSCLC) in adults. It will also learn about the safety of AMT-116. The main questions it aims to answer are: * Which level of AMT-116 works better to treat advanced or metastatic non-squamous EGFR-Wildtype NSCLC? * What medical problems do participants have when taking AMT-116? The goal of phase 3 of this clinical trial is to compare AMT-116 to study doctor's choice (a kind of retainable treatment for you in the opinion of the study doctor) to see if AMT-116 works better to treat advanced or metastatic non-squamous EGFR-Wildtype NSCLC. In both parts of this trial, participants will receive AMT-116 or study doctor's choice every 2 weeks until the study doctor thinks you are benefiting from your participation or until your disease progresses or you are unable to tolerate the study drug
This description comes directly from the study's public registry record.
Yanhong Fu · +86 13952922547 · yanhong.fu@multitudetherapeutics.com
Always discuss trial participation with your own doctor first.
| Coffs Harbour Health Campus | Coffs Harbour, Australia | — |
| Austin Health (Olivia Newton John Cancer Centre) | Melbourne, Australia | — |
| St Vincent's Hospital Melbourne | Melbourne, Australia | — |
| Calvary Mater Newcastle | Newcastle, Australia | — |
| Macquarie University Hospital | Sydney, Australia | — |
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Source record: clinicaltrials.gov/study/NCT07718737