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Study identifier: NCT07718581 Synced from ClinicalTrials.gov · July 28, 2026
● Not Yet Recruiting

HMPL-A830 in Solid Tumors

Condition: Solid Tumor, Adult  ·  Sponsor: Hutchmed

PhasePhase 1/Phase 2
Planned participants147
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human (FIH), multicenter, open-label, phase I/Ⅱa clinical study of HMPL-A830 in participants with histologically or cytologically confirmed, unresectable, advanced, or metastatic solid tumors\*, who are refractory or progressed on/after available standard treatment. The study will be conducted in 2 parts: Dose Escalation (Part A, Phase I), approximately 57 participants will be enrolled. Dose Optimization (Part B, Phase IIa), approximately 90 participants will be enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (7)

Beijing Cancer HospitalBeijing, China
Hunan Cancer HospitalChangsha, China
West China Hospital of Sichuan UniversityChengdu, China
The Sixth Affiliated Hospital,Sun Yat-sen UniversityGuangzhou, China
Shandong Cancer HospitalJinan, China
Jiangsu Province HospitalNanjing, China
Shanxi Provincial Cancer HospitialTaiyuan, China

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Source record: clinicaltrials.gov/study/NCT07718581