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Study identifier: NCT07718295 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HFNO Versus Face Mask for Cerebral Oxygenation During Procedural Sedation

Condition: Procedural Sedation · Hypoxemia · Cerebral Oxygenation  ·  Sponsor: Firat University

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective randomized controlled trial aims to compare the effects of high-flow nasal oxygen (HFNO) and conventional face mask oxygen therapy on cerebral oxygenation during procedural sedation performed outside the operating room. Adult patients undergoing elective diagnostic or interventional procedures under procedural sedation will be randomly assigned to receive either HFNO or conventional face mask oxygen. Regional cerebral oxygen saturation will be continuously monitored using near-infrared spectroscopy (NIRS), while sedation depth will be assessed using the Patient State Index (PSI, SedLine) and the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale. Secondary outcomes include peripheral oxygenation, ventilation parameters, arterial blood gas values, airway interventions, hemodynamic variables, and patient and practitioner satisfaction.

This description comes directly from the study's public registry record.

Talk to the study team

Ahmet Aksu, Assistant Professor  ·  +905303493896  ·  drahmetaksu@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fırat University Faculty of Medicine HospitalElâzığ, Elâzığ, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07718295